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Test Code CTP0 Catecholamine Fractionation, Supine, Plasma, Free


Specimen Required


Only orderable as part of profile. For more information see CATPA / Catecholamine, Endocrine Study, Plasma.

 

Patient Preparation:

1. Discontinue drugs that release epinephrine, norepinephrine, or dopamine, or hinder their metabolism, for at least 1 week before obtaining the specimen (see Cautions for details). If this is not possible for medical reasons, contact the laboratory and discuss whether a shorter drug-withdrawal period may be possible in a particular case.

2. Unless the purpose of the measurement is drug monitoring, discontinue any epinephrine, norepinephrine, or dopamine injections/infusions for at least 12 hours before specimen draw.

3. The patient must refrain from eating, using tobacco, and drinking caffeinated beverages for at least 4 hours before the specimen is collected.

Supplies: Catecholamine tubes containing EDTA-sodium metabisulfite solution (T066) (tubes have a 6-month. expiration time)

Collection Container/Tube:

Preferred: 10-mL Catecholamine tubes containing EDTA-sodium metabisulfite solution

Acceptable: 6-mL Catecholamine tubes containing EDTA-sodium metabisulfite solution

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL per collection

Collection Instructions:

1. Drawing from a catheter is required.

2. Calm the patient by giving complete instructions and reassurance regarding the procedure.

3. Insert an indwelling intravenous catheter. Flush with 3 mL of saline, using positive pressure.

4. Have the patient rest for 30 minutes in the supine position in a quiet room.

5. At the end of the 30 minutes, withdraw and discard a minimum of 3 mL of blood to remove the saline out of the catheter.

6. If provocative sampling (eg, standing specimen) is required, perform provocative maneuver immediately after obtaining supine specimen. Obtain standing specimen immediately.

7. For each specimen, draw blood into the chilled EDTA-sodium metabisulfite 10-mL tube.

8. Specimen must remain at refrigerated temperature during processing and transport.

9. Separate plasma in a refrigerated centrifuge within 30 minutes of draw.

10. Freeze specimen immediately.


Useful For

Diagnosis of pheochromocytoma and paraganglioma in specimens collected from individuals in a supine position, as an auxiliary test to fractionated plasma and urine metanephrine measurements

 

Diagnosis and follow-up of patients with neuroblastoma and related tumors, as an auxiliary test to urine vanillylmandelic acid and homovanillic acid measurements

 

Evaluation of patients with autonomic dysfunction/failure or autonomic neuropathy

Method Name

Only orderable as part of profile. For more information see CATPA / Catecholamine, Endocrine Study, Plasma.

 

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Catecholamine, Fract, Supine, P

Specimen Type

Plasma EDTA Meta

Specimen Minimum Volume

4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Meta Frozen 28 days

Reference Values

Only orderable as part of a profile. For more information see CATPA / Catecholamine, Endocrine Study, Plasma.

Day(s) Performed

Monday through Friday

Report Available

2 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82384

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CTP0 Catecholamine, Fract, Supine, P 95056-8

 

Result ID Test Result Name Result LOINC Value
33862 Norepinephrine, Supine 1601-4
33863 Epinephrine, Supine 1465-4
33864 Dopamine, Supine 95053-5