Intended Use

Used to aid in the diagnosis of hepatitis B virus in unvaccinated patients and to determine the immune status of vaccinated patients. Anti-HBs generally remains detectable in a HBV-exposed individual indefinitely, engendering immunity to future infections with HBV. However, in some patients, anti-HBs can decrease below detectable thresholds, but this does not necessarily correlate with loss of immunity to HBV as levels may quickly reach a detectable threshold following HBV re-exposure. During this period of undetectable anti-HBs, Anti-HBc (total) may be the only detectable serological marker for HBV infection.